Clindamycin suppresses virulence expression in inducible clindamycin-resistant Staphylococcus aureus strains
نویسندگان
چکیده
منابع مشابه
Failure of clindamycin treatment of methicillin-resistant Staphylococcus aureus expressing inducible clindamycin resistance in vitro.
We report a case of a surgical site infection caused by clindamycin-susceptible, erythromycin-resistant methicillin-resistant Staphylococcus aureus (MRSA) that did not respond to treatment with clindamycin. The MRSA isolate obtained after treatment was resistant to clindamycin but was found to be identical by pulsed-field gel electrophoresis to the clindamycin-susceptible isolate obtained befor...
متن کاملInducible clindamycin resistance among Staphylococcus aureus isolates
Introduction: Clindamycin is considered an useful alternate drug in penicillin-allergic patients in the treatment of skin & soft tissue infections caused by Staphylococcus aureus. Staphylococcus spp. can be resistant to erythromycin through either erm or msr A genes. Strains with erm-mediated erythromycin resistance may possess inducible clindamycin resistance but may appear susceptible to clin...
متن کاملPrevalence of clindamycin-resistant Staphylococcus aureus induced by macrolide resistance
Introduction: Since the incidence of various infections caused by Staphylococcus aureus increases, the use of effective antibiotics such as clindamycin has been growing to treat the systemic and local infections caused by such organisms. Antibiotic-resistant species are emerging and spreading in today's communities due to misuse of antibiotics and incomplete treatment, turning into a serious ch...
متن کاملInducible Clindamycin Resistance in Staphylococcus aureus Isolated from Clinical Samples
Increasing frequency of methicillin resistant Staphylococcus aureus (MRSA) infections and changing patterns in antimicrobial resistance have led to renewed interest in the use of macrolide-lincosamide-streptogramin (MLS) antibiotics to treat such infections. Inducible macrolides, lincosamides, type B streptogramins (MLS(Bi)) resistance has to be identified to avoid clinical failure of clindamyc...
متن کاملInducible clindamycin resistance in clinical isolates of Staphylococcus aureus.
Background: Staphylococcus aureus is one of the most important agents causing nosocomial infections. Inducible clindamycin resistance is an important concern, because common laboratory tests could not detect it. Objectives: The aim of this study was to detect the inducible clindamycin resistance by D-test method. Materials and Methods: A total of 209 clinical S. aureus isolates were collected a...
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ژورنال
عنوان ژورنال: Annals of Clinical Microbiology and Antimicrobials
سال: 2018
ISSN: 1476-0711
DOI: 10.1186/s12941-018-0291-8